Normal vs Optimal: A Physician’s Perspective
Many of us leave our annual physical reassured that everything is “normal.”
Yet normal does not always mean optimal.
Over time, energy declines, recovery slows, sleep becomes less restorative, and strength becomes harder to maintain. These changes are often accepted as inevitable, but physiology tells a more nuanced story.
Routine laboratory testing is designed to detect disease. It is less helpful in identifying early metabolic changes, low-grade inflammation, or hormonal shifts that influence how we function long before illness appears.
Recently, I decided to look deeper at my own health data using an advanced biomarker panel. The experience was both illuminating and instructive — not just because it revealed disease (it did), but because it highlighted opportunities to improve long-term vitality and function.
Gap in Traditional Wellness Programs
Over the years, I’ve also worked closely with employee health and workplace wellness programs. Many are well-intentioned but highly generic — built around annual screenings, health risk questionnaires, and familiar lab panels such as a CBC, chemistry profile, lipids, and fasting glucose. These tools identify established disease risk, but they rarely provide meaningful insight into early metabolic dysfunction, inflammation, recovery capacity, or resilience.
Biomarkers as the Next Evolution
Increasingly, biomarkers are entering conversations in occupational and employee health — from cardiovascular risk screening to more advanced surveillance in high-risk professions such as firefighting. The question is no longer whether data matters, but how to use it to improve function, safety, and long-term health.
Advanced biomarker panels offer a more nuanced view of physiology. They can identify early inflammatory changes, insulin resistance, lipid particle risk, micronutrient deficiencies, and hormonal shifts that influence energy, recovery, and long-term cardiovascular risk.
This deeper layer of insight has implications not only for individual longevity but also for workforce resilience, fatigue mitigation, and injury risk reduction.
As the workforce ages and chronic metabolic conditions become more prevalent, employers are beginning to explore health strategies that move beyond annual screenings toward earlier risk detection and functional health optimization. Platforms offering advanced biomarker testing — including team-based options — are emerging as one potential tool in this evolution.
The testing platform I used also offers an employer-focused model designed to help organizations better understand health risks within their workforce while providing individualized guidance. I plan to explore what this type of approach might mean for employers, safety-sensitive occupations, and workforce vitality in future issues.
My Experience Using Superpower
After enrolling in the Superpower program, I was scheduled for a blood draw at a local Quest Diagnostics draw station. The process was straightforward and familiar — clinically routine, but framed within a broader longevity and optimization model rather than a traditional annual physical.
A few days before the appointment, I received a preparation email outlining fasting instructions, foods to avoid, and other factors that could influence results. That detail immediately reinforced an important point: context matters. Biomarkers are only as useful as the conditions under which they are measured.
Shortly after the blood draw, I received a note from Dr. Vinjamoori, the company’s Chief Longevity Officer, outlining what to expect next — timing of results, how the biomarker report would be structured, and how my individualized action plan would be developed. That early communication set expectations clearly and positioned the experience as an ongoing process rather than a one-time lab event.

While waiting for results, I was given access to their full biomarker library — descriptions of more than 100 markers included in the panel. Reviewing that library alone was instructive. Many of the tests extended beyond the standard CBC, comprehensive metabolic panel, lipid profile, and fasting glucose that most of us are accustomed to seeing. Some markers I track regularly. Others I have rarely paid attention to. A few were entirely new to me.
Their educational newsletter model was also noteworthy. Each edition focuses on a specific biomarker and then translates that data into activity, nutrition, and lifestyle considerations. It reflects a broader shift in medicine — moving from identifying disease toward understanding physiology.
My results returned within just a few days. I received both a detailed PDF report and access to an online portal. Each biomarker included:
What the test measures
Why it matters
Where I fell relative to optimal and standard ranges
Practical interpretation
In addition, I received a structured “protocol” outlining high- and medium-priority areas, along with lifestyle, nutrition, and supplement recommendations tailored to my specific risk profile.

With over 100 biomarkers analyzed, this was more than a lab report — it was an education. Even as a physician, I found myself studying markers I had not previously emphasized and considering relationships between inflammation, metabolic health, recovery, micronutrients, and long-term function in a more integrated way.
What We’ll Unpack in Upcoming Issues
In the coming weeks, I’ll begin breaking down specific areas of this panel in detail — particularly the categories that have the greatest implications for both personal vitality and workforce resilience.
We’ll explore:
Inflammatory Markers
How low-grade inflammation influences cardiovascular risk, musculoskeletal health, fatigue, and long-term aging trajectories — and what meaningfully moves these numbers.
Advanced Lipid & Cardiovascular Risk Markers
Beyond LDL cholesterol — including particle risk and transport markers — and how these relate to metabolic function and endurance.
Hormonal & Recovery Signals
Markers tied to muscle preservation, energy, stress physiology, and resilience — particularly relevant as we age.
Micronutrients & Cellular Health
Often overlooked drivers of energy, cognition, immune function, and recovery capacity.
For each, we’ll examine three things:
What the biomarker truly reflects physiologically
What influences it
What is realistically worth doing next
The objective is early pattern recognition, practical adjustment, and maintaining strength and resilience over time.
What This Could Mean for Employers
One aspect that particularly interests me is how this model translates to workforce health.
Many employer wellness programs still rely on annual biometric screenings built around basic labs — cholesterol, glucose, blood pressure — often delivered without longitudinal insight or individualized interpretation. In safety-sensitive industries, certain biomarkers are tracked for surveillance purposes, yet rarely integrated into a broader physiological strategy.
Platforms offering more comprehensive biomarker panels — including team-based models — create an opportunity to shift from generic screening to early risk detection and performance-oriented health strategy. For employers facing rising metabolic disease, fatigue-related risk, and an aging workforce, this may represent an evolution worth exploring.
In future issues, I will examine how advanced biomarker programs could be structured responsibly within workforce settings — including ethical considerations, privacy, and practical implementation.
Interested in Exploring This for Yourself?
If you are curious about undergoing advanced biomarker testing yourself, you can explore the same platform I used.
I’ve partnered with Superpower as an affiliate. If you choose to enroll through my link, I may receive a commission at no additional cost to you.
Before you do that, I’ve created the Advanced Biomarker Preparation Guide to help you think through:
Whether advanced biomarker testing is appropriate for you
How to prepare for meaningful results
How to interpret “normal” vs optimal ranges
What questions to ask before enrolling
You can access that free guide here:
Download the Advanced Biomarker Preparation Guide:
(You’ll enter your email to receive it.)
After reviewing the guide, you can decide whether to proceed with testing.
If you know you’re ready to jump in:
